The State Prize for the Promotion of Alternative Methods to Animal Testing 2024 goes to a team led by biologist Prof. Jürgen Knoblich from the Institute of Molecular Biotechnology (IMBA).
Using melanoma cells from patients, a research team from the University of Regensburg has observed that during early metastasis of skin cancer cells, an embryonic stem cell program is activated as a defense against the body's own immune response. The body's own defenses are weakened and the cancer can spread to the new tissue.
Researchers from ETH Zurich led by Pedro Beltrao, Professor at the Institute of Molecular Systems Biology, have presented an atlas that shows which proteins work together in which tissues. These findings help to identify disease genes more specifically and to develop drugs that act specifically at the target site.
A team of researchers from the Max Planck Institute of Molecular Physiology (MPI) in Dortmund, led by Dr. Malte Gersch, has used cell cultures to elucidate the mode of action of a promising Parkinson's drug candidate. The work serves as a basis for the development of targeted therapies against Parkinson's disease.
A team of scientists from Luxembourg Centre for Systems Biomedicine (LCSB) led by Prof. Christian Schwamborn has presented a promising midbrain-hindbrain assembloid model that can be used to mimic the spread of alpha-synuclein pathology as observed in Parkinson's patients.
Humane World for Animals is seeking nominations for the Humane Science Innovator Award, formerly known as the Russell and Burch Award. The award is given to scientists who have made outstanding contributions to the replacement of animals in research and testing.
Researchers at the Technical University of Darmstadt, the NMI Natural and Medical Sciences Institute in Reutlingen, as well as from the Black Drop Biodrucker company have developed a new type of bioink that improves nutrient transport in printed tissue.
The National Institutes of Health (NIH) is starting a new initiative to expand innovative, human-based science while reducing the use of animals in research.
With the help of in vitro tests, American scientists have been able to observe that it is not nicotine that is responsible for the atherosclerotic effect of tobacco smoking, but presumably the countless other harmful substances that enter the circulation through the inhalation of combustion products.
Instead of clear rules for phasing out animal experiments in accordance with the reduction strategy that has been drawn up, the current coalition government is now planning a separate law that would exclude animals in experiments from the Animal Welfare Act. This would have serious consequences for their protection.