News
Infection mechanism: coronavirus can infect neighbouring cells via filipodia
Monday, 29 June 2020 15:24An American research team from the University of California has observed in vitro that cells infected with SARS-CoV2 can infect their neighbors with the coronavirus via filipodia - thread-like protuberances of the cells - before they are eliminated by the immune system.
DNT: Mixtures can be more harmful than individual chemicals
Monday, 29 June 2020 10:40Using cell cultures and a mathematical model, scientists at the European Union's Joint Research Centre have found that the effects of chemical mixtures on the developing human brain can be more harmful than the sum of the individual chemical effects determined in tests.
EPA presents work plan for the gradual reduction of animal testing for the risk assessment of chemicals
Friday, 26 June 2020 09:01The US Environmental Protection Agency's (EPA) work plan for the use of New Approach Methods (NAMs) was developed in response to EPA Administrator Andrew Wheeler's Guideline 2019, which aims to reduce the use of animal testing while maintaining the protection of humans and the environment.
CAAT Summer School: some events free of charge
Tuesday, 23 June 2020 10:09The online Summer School of the Center for Alternatives to Animal Testing (CAAT) at the Johns Hopkins Bloomberg School of Public Health in Baltimore is currently running.
Some of the events can be attended free of charge.
Empa: Using cell cultures and algorithms to analyze the risk of nanoparticles
Tuesday, 23 June 2020 09:55Scientists at Empa in St. Gallen, Switzerland, are using cell cultures as well as mathematical comparison models and algorithms to determine the risks of nanoparticles, especially of Graphene, on humans.
Coronavirus is able to infect brain cells
Thursday, 18 June 2020 13:32Scientists at the Center for Alternatives to Animal Testing (CAAT) at the Johns Hopkins Bloomberg School of Public Health in Baltimore have used an in vitro model to find out that the coronavirus SARS-CoV-2 can infect the human brain and multiply in the brain's nerve cells.
Fraunhofer Institutes develop immunocompetent Covid-19 infection model
Monday, 15 June 2020 12:58The Fraunhofer Institutes IGB, IZI, and IME as wells as the company Dynamic42 combine their competences and develop an immunocompetent lung-on-a-chip with human lung cells. With the model, they want to investigate the efficacy against SARS-Cov-2 of up to 40 different drugs from Fraunhofer libraries.
Gastroloid: researchers have designed model of early human development
Thursday, 11 June 2020 15:48A British-Dutch research team has developed a new model of human embryonic stem cells (gastroloid) to study an early stage of human development.
Read-across is most commonly used: The use of alternatives to animal testing in chemical safety
Thursday, 11 June 2020 12:11In its current report 2020, the European Chemicals Agency (ECHA) informs, that there have been some changes in the use of alternatives to animal testing compared to the last study in 2017.
Immunocompetent 3-organ chip model for immune studies in multisystemic diseases
Monday, 08 June 2020 10:29A peer-reviewed study by Hesperos Inc. based in Florida reports on how the company's human-on-a-chip technology can be used to study immune responses to treatment with biological therapeutics in multi-organ systemic diseases.
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