Bonn: Blood cells become nerve cells

Tuesday, 23 October 2018 11:09

Researchers from the Institute for Reconstructive Neurobiology at the University of Bonn, the German Centre for Neurodegenerative Neuroscience (Deutsches Zentrum für Neurodegenerative Diseases (DZNE) Bonn, together with other colleagues from the Universities of Bonn, Aachen and Munich, has succeeded in converting white blood cells directly into neuronal stem cells without the time-consuming process of inducing pluripotent cells (iPSC).

Organs on demand for medical training

Monday, 22 October 2018 11:33

The Karl Landsteiner Private University for Health Sciences in Krems/Danube has started a research project. With a 3D printer the researchers want to print realistic organ models for research and medical training.

Scientists headed by Dr Udo Klotzbach, Business Unit Manager Microtechnology at Fraunhofer IWS in Dresden have received the Innovation Award of the European Association of Research and Technology Organisations (EARTO). The organisation honoured the scientists for their development of a multi-organ chip system, on which tiny organs connected by a blood circulation system can be reproduced.

Prof. Thomas Hartung, director of the Center for Alternatives to Animal Testing (CAAT) at Johns Hopkings University in Baltimore, and his team have developed a computer program that enables them to predict the toxicity of chemicals better than with animal experiments.

The this year's Animal Welfare Research Prize of the Federal Ministry of Agriculture (BMEL) is awarded to Professor Dirk Görlich and Dr Tino Pleiner from the Max Planck Institute for Biophysical Chemistry in Göttingen. The scientists have developed a method that can replace the production of secondary antibodies in animals. The two scientists have succeeded in developing a new type of antibody, so-called secondary nanobodies, which can be multiplied without the use of animals.

The JRC's EU Reference Laboratory for alternatives to animal testing (EURL ECVAM) has launched a second call for tender to review alternative methods and models being used for research in the areas of Cardiovascular diseases, Breast Cancer, Immunogenicity testing for advanced therapy medicinal products, Autoimmune diseases and Immune Oncology Models.

The Society of Toxicology (SOT) is accepting applications through Monday, October 9, for the following grant opportunities.

Hormone-disrupting chemicals in our environment can affect early neurodevelopment in children, but little is known about the exact mechanisms for this interference. A new EU funded research project, coordinated from Karolinska Institutet, now aims to learn more and to develop better screening and testing tools.

Using a cell line as well as nerve precursor cells, scientists from the University of Munich (TUM) and from the Max Planck Institute for Biochemistry (MPI-B) have discovered the mechanism that leads to microcephaly caused by a Zika virus infection.

InVitro+Jobs regularly presents scientists and their innovative research. The focus is on newly developed methods, their evaluation as well as an outlook, which animal experimental approaches according to the 3R principles (reduce, refine, replace) can be reduced and preferably replaced.

This time we present the state of development in reproductive and developmental toxicology.

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