A scientist from the Karlsruhe Institute of Technology (KIT) estimates that it could take approximately 20 years before the animal experiments in the field of drug development can be replaced by multi-organ chips.

The European Reference Laboratory for alternatives to animal testing (EURL-ECVAM) has launched a validation study evaluating in vitro methods that are able to detect endocrine disruptive chemicals. In the validation study, 17 different in vitro methods are considered as candidates.

The American Institute for In Vitro Sciences (IIVS) has currently opened a laboratory for in vitro respiration studies. To start inhalation toxicology studies, IIVS received a in vitro exposure system. With the new device, the scientists want to investigate the effects of new cigarette products, such as the next generation heat-not-burn systems and e-cigarettes on human lung cells.

In a consultation paper on a reform of the Australian Chemicals Directive (National Industrial Chemicals Notification and Assessment Scheme, NICNAS) the Health Department of the Australian Government provides a ban for the production and marketing of "cosmetic chemicals" tested on animals in Australia from the first of July 2018 onwards. Cosmetic chemicals are those which are used solely for cosmetic purposes.

Animal-Free Research UK (formerly Dr. Hadwen Trust), the largest British foundation for animal-free medical research has invested 3.2 million pounds in research during the past 5 years and compiled a database of commercially available serum-free media, available as a resource for researchers around the world looking for suitable media. Goal is to replace the fetal calf sera as quick as possible. Together with the 3R-Centre Utrecht Life Sciences the database will be launched with a short opening ceremony in Utrecht.

During the annual meeting in Halle (Saale) the senate of the German Research Foundation (DFG) has decided to support a funding initiative to promote sequencing projects - and the associated expansion of the infrastructure at universities.

A researcher team from the Martin Luther University Halle examine an intrinsically disordered protein in the human body. Intrinsically disordered proteins are such do not have a solid structure. They are located at switching sites of the cells' signal processing and can be misused by tumor cells to metastasize.

FADU method for space research

Wednesday, 05 July 2017 12:51

The biologist Dr. Maria Moreno-Villanueva from the Department of Molecular Toxicology at Konstanz University receives a grant from NASA's Johnson Space Center in the amount of 10,000 US dollars to improve an automated diagnostic device for DNA damage for space research.

The pharmaceutical company AstraZeneca has developed a screening platform in which heart micro tissues have been combined with high-throughput imaging. Thus it is possible to better detect potential cardiotoxic indications during drug development.

To investigate adverse immune responses to dental and laryngeal implants, an international research consortium, co-ordinated by the Steinbeis 2i GmbH has developed a foreign body response on-a-chip platform. Such kind of diagnostic test can predict individual immune responses of individual patients.