Using a collection of historical human blood samples, researchers from the Institute of Medical Virology at the University of Zurich have discovered that the severity of an infection such as COVID-19 is caused by autoantibodies. These are autoantibodies that neutralize type I interferons (IFN-Is).

The renowned researcher Prof. Milica Radisic from the Institute of Biomedical Engineering at the University of Toronto will be working at the Max Delbrück Center in Berlin-Buch for the next three years with the aim of equipping organoids with blood vessels. This would make them more similar to a real organ in miniature format.

At its 179th meeting in June 2024, the Ph.Eur. Commission adopted 57 revised texts aimed to completely remove the test for fever-inducing substances in rabbits (pyrogen test) from the European Pharmacopoeia (Ph.Eur.). This means that the use of the pyrogen test in rabbits is no longer prescribed anywhere in the regulations.

Pepper has issued a call for “testing laboratories” for the validation of “Fluorescent FITC-T4 Transthyretin Competitive Binding Assay for endocrine disruptors”.

The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) is now accepting proposals for the 2024 Reduction and Humane Education Grants.

A research team from the Department of Stem Cell & Regenerative Biology at Harvard University in Cambridge and from the Broad Institute at MIT in Harvard as well as other colleagues have developed a multi-donor organoid model of the human cerebral cortex.

Two projects in the field of cancer research led by Prof. Dr. Alexander Kleger, Ulm University Medical Center, as well as Dr. Vidhya Madapusi Ravi from Freiburg University Medical Center are being funded. 

Havard: Cervix on a chip

Monday, 17 June 2024 11:02

A team of researchers led by Prof. Donald E. Ingber from the Wyss Institute for Biologically Inspired Engineering at Harvard University in Boston has developed an organ-on-a-chip model that can replicate the human cervix with a functional epithelial barrier and mucus production featuring biochemical and hormone-dependent properties similar to the living cervix.

With the help of engineered human respiratory epithelial organoids, a team from the University of Basel has succeeded in observing how the bacterium Pseudomonas aeroginosa manages to break through the lung barrier. This bacterium targets certain cells in the lungs and has developed a tactic to break through the line of defense.

Researchers at the Institute of Biomechanics at ETH Zurich have developed a 3D in vitro model to study brittle bone disease in more detail to mimic the dynamic process during early bone formation.