Research teams from Würzburg and Braunschweig have discovered a novel mechanism of a protein that counteracts the CRISPR/Cas process. It can be used to specifically control CRISPR technologies.
The organ-on-a-chip developer Dynamic42 from Jena, ESQlabs, experts in digital solutions for life sciences, in close collaboration with Bayer's Consumer Health Division and the placental laboratory of the University Hospital Jena have successfully developed a three-organ system. The model has the potential to significantly reduce animal testing using organ-on-chip (OoC) technology and interactive computer software.
A European research team has developed an adipose tissue portal with molecular and clinical data from more than 6,000 women and men from 67 studies. The researchers want to facilitate research into obesity and metabolic diseases by centralizing and simplifying access to data on adipose tissue.
With this funding measure, the BMBF (Federal Ministry of Education and Research) is pursuing the goal of implementing the process of drug research faster and with a higher success rate in the future along the entire development chain using AI.
Prof. Frank Edenhofer, head of the Genomics, Stem Cell Biology and Regenerative Medicine research group at the University of Innsbruck, and his team have developed a human tissue model that can be used to watch the brain aging process.
The aim of standardization is to ensure that organ-on-a-chip devices can be used reliably and effectively for the development of new drugs, in personalized medicine and for safety testing of chemicals and consumer products such as cosmetics.
The European Union Reference Laboratory for alternatives to animal testing (ECVAM) has presented a virtual laboratory developed for pupils aged between 14 and 18, but also for older school children. In a 20-minute film, a professor guides the "students" through research into a new alternative to animal testing.
The European Validation Authority EURL ECVAM offers users open access to its High-Throughput Testing laboratory.
Using heart organoids, researchers from the Genomic Medicine Center and Children's Mercy Research Institute, the University of Missouri-Kansas City School of Medicine and the University of Kansas Medical Center in Kansas City have demonstrated the efficacy of their antisense oligonucleotides in patients.
What specifically happens when developing nerve cells are exposed to “chronic” stress has been investigated by researchers at the Max Planck Institute of Psychiatry in Munich using cell models of the developing brain.