Researchers at the Technical University of Darmstadt, the NMI Natural and Medical Sciences Institute in Reutlingen, as well as from the Black Drop Biodrucker company have developed a new type of bioink that improves nutrient transport in printed tissue.
The National Institutes of Health (NIH) is starting a new initiative to expand innovative, human-based science while reducing the use of animals in research.
With the help of in vitro tests, American scientists have been able to observe that it is not nicotine that is responsible for the atherosclerotic effect of tobacco smoking, but presumably the countless other harmful substances that enter the circulation through the inhalation of combustion products.
Instead of clear rules for phasing out animal experiments in accordance with the reduction strategy that has been drawn up, the current coalition government is now planning a separate law that would exclude animals in experiments from the Animal Welfare Act. This would have serious consequences for their protection.
On Tuesday, April 22, the Federal Ministry of Food and Agriculture's (BMEL) newly conceived Animal Welfare Research Prize was awarded to two winners. This year's winners are the organoid researcher and molecular geneticist at the University of Utrecht, Prof. Dr. Hans Clevers, and the well-known refinement researcher Prof. Dr. Adrian Smith - known for the norecopa platform and the arrive guidelines for improving the planning of animal experiments. A national prize for young scientists for methods and procedures to replace or reduce animal experiments was not awarded - there were too few applications.
According to the Washington Times, Lee Zeldin, head of the U.S. Environmental Protection Agency (EPA), plans to revive a ban on animal testing at the Environmental Protection Agency.
Using a genome-wide association study (GWAS) on osteoarthritis, an international research team led by Prof. Dr. Eleftheria Zeggini, Director of the Institute of Translational Genomics at the Helmholtz Zentrum München, has identified hundreds of new drug targets. The results also revealed possibilities for repurposing existing therapies.
A research team from the Vrije Universiteit Amsterdam, the Netherlands, in collaboration with the Berlin-based company TissUse GmbH, Germany, has developed a functioning perfused vascular system on a microchip. The development of mini-organs with functioning blood vessels had not been addressed in a focused way before, so this gap in physiological tissue and organ models may now be closed.
A bioveterinary institute in Wageningen, the Netherlands, is one of the first institutes to switch its botulism diagnostics to a new animal-free in vitro test method, thus replacing the mouse bioassay.
Every two years, the German Centre for the Protection of Laboratory Animals (Bf3R) at the German Federal Institute for Risk Assessment (BfR) awards funds for scientific research projects in accordance with the 3R principle (Replace, Reduce, Refine) primarily to young scientists. With an annual total budget of approximately 350,000 euro, innovative projects of high scientific quality are funded for a total duration of up to 3 years.