Together with scientists from the University of Central Florida, Hesperos Inc. in Orlando has developed a model of peripheral myelination derived from human induced pluripotent stem cells. It enables research into therapies for currently incurable diseases of the peripheral nervous system, such as Charcot-Marie-Tooth disease or Guillain-Barré syndrome.
On October 25, the European Commission hosted the second conference on the roadmap for phasing out animal testing in the safety assessment of chemicals. The focus was on bringing order to the objectives, accelerating recognition and securing funding.
VICT3R (Developing and implementing VIrtual Control groups To reducE animal use in toxicology Research) is a public-private partnership funded by the European Innovative Health Initiative (IHI). The aim is to reduce animal use in toxicology research, improve scientific results and maintain higher ethical standards.
Researchers at the Berlin Institute of Health (BIH) have received funding form European Research Council (ERC). For their studies, they are using human induced pluripotent stem cells.
On October 9, 2024, a virtual event was held by the Federal Network 3R. Its topic this time was “Artificial intelligence and in-silico - trends in 3R research”. Numerous presentations were followed by a panel discussion with Prof. Lars Küpfer from the University Hospital Aachen, Charlott Danielson, from Fraunhofer Research Institution for for Individualized and Cell-based Medical Engineering IMTE, Dr. Sylvia Escher from Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Dr. Andreas Göller, Senior Science Fellow Computational Chemistry at Bayer AG as well as Prof. Thomas Hartung from the Center for Alternatives to Animal Testing (CAAT) at Johns Hopkins University in Baltimore.
As the animal rights organization PETA USA reports in a recent press release, the international pharmaceutical giant Sanofi has decided to no longer carry out so-called forced swim tests with rats or mice.
The European Commission has published the expert report on the Human Brain Project (HBP). The EU flagship initiative to research the human brain ended in 2023 after a ten-year period.
Elsevier, the publisher of scientific journals, has launched a new open access journal. It sees itself as a hub for the dissemination and global exchange of information on the latest NAM developments.
Most people interested in animal-free methods probably don't have the opportunity to go to a laboratory and be shown and explained the new methods. A movie can replace this. A clear explanation with moving images makes it easier to understand the new techniques and raise awareness that there are methods other than animal testing. In his film, the enthusiastic filmmaker Marc Pierschel lets well-known researchers have their say, presenting their developments and explaining them in a vivid way.
A team at Kyoto University has developed a human induced pluripotent stem cell-derived proximal tubule-on-chip (OPTECs-on-chip). It has the necessary functionality and polarity of important kidney transporters. According to the developers, the kidney chip model can therefore be used to assess drug transport and nephrotoxicity.