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Scientists at the Max Delbrück Center for Molecular Medicine (MDC), Berlin-Buch, and at the European Molecular Biology Laboratory (EMBL), Heidelberg, have developed an AI that can increasingly elucidate the cellular mechanisms involved in the development of cancer.

IUCLID database to avoid animal testing

Sunday, 29 January 2023 20:03

IUCLID (International Uniform ChemicaL Information Database) is a software application for collecting, storing, maintaining and exchanging data on intrinsic and hazardous properties of chemical substances. Such data play an important role in chemical regulation by both industry and regulatory agencies.

As part of its commitment to support the transition to an animal-free regulatory system, from the 31st of May to the 1st of June, ECHA is organizing a workshop to discuss critical needs to enable faster progress.

The federal government is funding the "Cellzero Meat" project with about 1.2 million euros. Cellzero Meat is a scientific network that is looking for alternatives to conventional meat production. The goal is to overcome the obstacles that have not yet been solved. To this end, the researchers want to close gaps in knowledge so that meat from the laboratory can be produced without antibiotics and in an animal-friendly way.

This time, two prestigious research awards from the Center for Alternative to Animal Testing (CAAT) at the Bloomberg School of Medicine in Baltimore go to two German teams for their commitment to non-animal methods.

Hamburg: In vitro researcher to hold 3Rs chair

Wednesday, 18 January 2023 10:42

Biomedical scientist Prof. Maike Frye takes over the chair on 3R methods at the University Medical Center Hamburg-Eppendorf (UKE). With her Vascular Biology group, the scientist is developing novel hydrogel techniques for culture systems of human cells. The aim is to recreate tissue environments of vascular endothelial cells. 

At the end of December 2022, U.S. President Joe Biden signed the "FDA Modernization Act 2.0." Under this law, it is no longer necessary to test the safety of drugs on animals in order to obtain approval from the U.S. Food and Drug Administration (FDA), the government agency that oversees food, drugs, and medical devices. This could initiate a significant reduction in animal testing after more than 80 years of safety testing of drugs on animals.

A team from Fraunhofer Institute for Material and Beam Technology IWS in Dresden as well as from Helmholtz-Zentrum Dresden-Rossendorf (HZDR) is using an organ-on-a-chip to explore the possibilities of fighting persistent tumors with the help of radioactive substances.

Rare muscle disease in the petri dish

Wednesday, 21 December 2022 13:43

Researchers from Göttingen have developed skeletal muscles from human stem cells in their laboratory. The goal is to be able to test the efficacy of drugs without animal testing.

When hungry: cell switches metabolism to fat

Friday, 16 December 2022 11:00

A team led by Prof. Volker Haucke and Dr. Wonyul Jang at the Leibniz Research Institute for Molecular Pharmacology (FMP) has discovered a previously unknown mechanism by which different compartments in the cell communicate with each other in such a way that cell metabolism is converted depending on the food supply.

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