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Scientist at the National Center for Translational Science (NCATS) at the NIH in Washington, D. C., want to use organ-on-a-chip systems of the start-up company Hesperos to identify the causes of the national opioid crisis.

Heterotopia model in the Petri dish

Wednesday, 20 March 2019 14:49

Scientists at the Max Planck Institute for Psychiatry have used brain organoids to simulate the hereditary disease heterotopia. During brain development, cell migration disorders lead to node-like accumulations of grey matter outside the cerebral cortex.

Organ-on-Chip applications in Basic Research, Pharmaceutical Drug Development, Safety assessment of Drugs, Cosmetics and Chemicals among others are facing an exponential arise in interest. Therefore, specific training is required on the production of such cell culture systems using advanced microfabrication techniques and adequate on-chip characterization of relevant cell functions.

A team of Swiss scientists from EAWAG in Dübendorf has developed a device that can be used to test the harmfulness of fragrances to the environment using intestinal cells. Thus, animal experiments in ecotoxicological experiments can be reduced. The device has also potential for drug development.

On Thursday, March 14th, there will be given a very interesting lecture on 3D printing of spherical organ-like systems at Institute of Biotechnology of the Technical University Berlin. The physician Dr. Vladimir Mironov from the Medical Sechenov University in Moscow will inform the audience about tissue spheroids as building blocks for robot-assisted biofabrication of three-dimensionally printed tissues.

Bf3R awards funding for feasibility studies

Wednesday, 06 March 2019 08:54

The German Centre for the Protection of Experimental Animals (Bf3R) awards funding for young scientists. The total budget is 350,000 euros with which up to 10 projects can be funded each year.

EUSAAT Congress in Linz postponed to October

Friday, 22 February 2019 10:42

Due to organisational reasons, the EUSAAT Congress on Alternatives to Animal Testing in Linz 2019 has been postponed from August to October 10 - 13, 2019.

Scientists of the German Cancer Consortium (DKTK)+ and the Georg-Speyer-Haus at Goethe University Frankfurt have discovered an intestinal tumor-specific molecular response chain triggered by the Wnt signalling pathway. For their work, the researchers used so-called intestinal organoids - mini intestines that they had developed from human intestinal tissue.

Scientists from the Department of Neuropathology at the University Hospital Regensburg led by Professor Markus Riemenschneider have developed tumour disease models in the form of organoids in the Petri dish. The  cells derived from tumour cells of patients. The researchers want to use this model to investigate the interaction between healthy cells and tumour cells in more detail and test new therapeutic methods.

Vanda Pharmaceuticals Inc. headquartered in Washington DC is suing Food and Drug Administration (FDA) because - according to the company - of the demand for a conduction of unnecessary drug tests on dogs.

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