Researchers at the University of Basel used the method of high-throughput metabolomics to simultaneously test the effects of more than 1,500 active substances on the metabolism of cells.

The Foundation for the Promotion of Research into Alternative and Complementary Methods to Animal Experiments (Stiftung zur Förderung der Erforschung von Ersatz- und Ergänzungsmethoden zum Tierversuch, set Foundation for short) is suspending its funding round this year.

Using a brain organoid model, a research team from the Department of Biomedical Engineering at Tufts University in Medford, Massachusetts, in collaboration with the University of Oxford, has observed that neuronal injury can reactivate latent herpes type 1 viruses, leading to the production and accumulation of ß-amyloid and phosphorylated tauproein, which promotes synaptic dysfunction and neurodegeneration.

A research team led by Prof. James Hickman of Hesperos Inc., in collaboration with the University of Central Florida in Orlando, has developed a novel multi-organ MPS model to investigate the efficacy and off-target toxicity of naloxone in combination with opioids.