News
Animal testing in Europe: First far more animal testing than planned
Tuesday, 01 August 2023 12:48Drafts updating the EU Chemicals Regulation indicate that the number of animal tests for safety assessment will rise sharply in the coming years. A new study confirms this and shows that the originally expected number of four million animals has already been exceeded.
Humain Award 2023
Wednesday, 19 July 2023 14:45Together with the Swiss company InSphero, the Physicians Committee for Responsible Medicine (PCRM) will present the HUMAIN Award to five laboratories. Goal is to expand access to human-specific non-animal approaches and accelerate their adoption.
JRC and EPAA provide information on their designathon for systemic human toxicity
Sunday, 16 July 2023 14:27The Joint Research Center of the European Union (JRC) and the European Partnership for Alternatives to Animal testing (EPAA) recently held an informational webinar on their designathon for the use of human-specific methods in systemic toxicity.
Basel: Arf1 coordinates fatty acid metabolism
Wednesday, 12 July 2023 14:42A research group led by Prof. Dr. Anne Spang of the Biozentrum of the University of Basel has investigated the lipid metabolism process in yeast cells and human cells. The team found that a protein called Arf1 influences when and how much stored fat is converted into energy.
Scourge malaria: exploring new treatments based on the chip
Wednesday, 12 July 2023 13:54To analyze malaria disease mechanisms and explore better treatment options, Hesperos, a company based in Orlando, Florida, has developed a malaria disease model on a chip that integrates four human tissue constructs. New treatments are urgently needed because the malaria pathogen has become resistant to drugs. To find new drugs more quickly and effectively, organ-on-a-chip technologies may be well suited.
Genome-wide association study: important clues to single nucleotide polymorphisms in multiple sclerosis
Wednesday, 12 July 2023 10:48As published online in Nature in late June, a study suggests that although the beginnings of multiple sclerosis are based on autoimmune disease, the progression of the disease in individual patients depends partly on how well the brain copes with the autoimmune attack.
Adiposity research with cells
Thursday, 06 July 2023 10:25A team of researchers led by Prof. Dr. Anne Spang from the Biozentrum of the University of Basel has studied the lipid metabolism process in yeast cells and human cells in more detail. They have discovered that the protein Arf1 (ADP-ribosylation factor 1) acts like a molecular switch to regulate how many lipids are converted into ATP in the body.
Disease model on a chip: researchers develop Barret's esophageal reflux disease
Thursday, 06 July 2023 09:10Scientists at the Wyss Institute at Harvard University in Boston have recreated a model of reflux disease (barrett's disease) in vitro. The goal is to gain a better understanding of the cellular and molecular triggers of this disease and to develop appropriate drug therapies.
Berlin: International Congress on Multiorgan-on-a-Chip with overwhelming contributions
Saturday, 01 July 2023 09:32This year's World Summit on Microphysiological Systems was held in Berlin from June 26 to 30. 1,297 participants from numerous countries had registered. It was impressive to see how many young scientists dedicated themselves to the development of animal-free methods with the ultimate goal of finding better treatments through human-specific research, reducing the financial burden and time required to do so, and replacing animal experimentation.
Bayer manager outlines steps to phase out animal testing
Friday, 23 June 2023 12:31Dr. Eckhard von Kreutz, former senior vice president and head of translational sciences at Bayer Pharmaceuticals, recently described on the LinkedIN platform eight steps necessary to completely replace animal testing.
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