The nigrostriatal pathway is one of the four most important dopamine pathways in the brain and plays a crucial role in movement execution as part of a system called the basal ganglia motor loop. How this circuit develops during human development and how it degenerates under pathological conditions is still largely unknown. A research team from Sweden, Denmark, as well as Switzerland has succeeded in developing an in vitro model (connectoid) to elucidate the mechanism.

The Mirror Group (MG) is an advisory body that provides recommendations and opinions on the implementation of the EPAA Action Program, on project proposals and project implementation, and on other ongoing tasks of the EPAA, such as public relations, communication, and dissemination of information. It acts as an interface between the EPAA partnership and expert groups, including those from science, (national) 3Rs centers, patient groups, animal research and animal welfare NGOs. It acts as a “multiplier” for the work of the EPAA.