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Multidisciplinary research at the Wyss Institute has led to the development of a multi-material 3D bioprinting method that generates vascularized tissues composed of living human cells that are nearly ten-fold thicker than previously engineered tissues and that can sustain their architecture and function for upwards of six weeks.

The Alternatives in Research Challenge

Thursday, 21 September 2017 08:38

The Alternatives in Research (AiR) Challenge is a program intended to stimulate innovative research that advances medical progress through the use of methods that do not involve animals.

An interesting overview on the current developments, challenges and perspectives of human on a chip platforms and disease models on a chip is given by researchers of the Berlin spin-off TissUse.

More than 60 percent of investigational drugs fail in human clinical trials due to a lack of effectiveness, despite promising pre-clinical studies using cell and animal research models. For this resason, the National Institutes of Health (NIH) are now promoting 13 research projects that have failed to prove effective. The has approved a two-year funding programme totalling $ 15 million per year.

With the help of a cell culture model consisting of patients' tumor cells, scientists from the cluster of excellence BIOSS Centre for Biological Signalling Studies at the University of Freiburg and the Freiburg University Medical Center have tested a new inhibitor which could be effective against a bad breast cancer prognosis.

The Journal Applied In Vitro Toxicology is going to launch a special Issue on "Implementing Alternative Approaches for Inhalation Toxicity Testing". Deadline for manuscript submission is December 15, 2017.

A team of scientists in the department Experimental Toxicology and Ecology at BASF SE in Ludwigshafen, Germany, has refined a method for detecting substances that can trigger allergic skin reactions. This allows the intensity of a substance’s skin-sensitizing effect to be predicted. This is important for assessing not only chemicals’ skin-sensitizing effects (H317) according to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), but also their potency (sub-categories 1A and 1B).

EPAA Prize: Deadline extended

Friday, 08 September 2017 12:16

The deadline of the this years`Refinement Prize of the European Partnership for Alternative Approaches to Animal Testing (EPAA) has just been extended. Applicants now have until end of September 22nd to submit their application for this €6000 award.

A collection of non-animal methods shall be provided in use for basic and applied research concerning the following four human disease areas: neurodegenerative diseases, respiratory tract diseases, cardiovascular diseases and breast cancer.

The PETA International Science Consortium Ltd. (PISC) is proud to announce an early-career scientist award to participate in the Institute for In Vitro Sciences’ (IIVS) 2018 Practical Methods for In Vitro Toxicology Workshop. The award will fund workshop registration ($1,950 USD), as well as airfare and hotel accommodations (up to $1,000 USD).