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A team of researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University in Boston has developed a more realistic model of inflammatory bowel disease on a chip, incorporating mucus production, barrier function, inflammatory responses, fibrosis, and cancer development. The goal was to replicate key pathophysiological features, inflammatory mechanisms, gender-specific effects, and cancer development in inflammatory bowel disease.

Researchers at the Swiss Federal Laboratories for Materials Science and Technology in Dübendorf, Switzerland, have developed an AI-powered computer model of a laboratory mouse that uses machine learning to predict how various nanomaterials distribute within the mouse’s body. In the future, the model is intended not only to serve as a decision-making tool in drug development but also to reduce the number of animal experiments. 

Researchers at the Helmholtz Zentrum München, the Technical University of Munich (TUM), the Stowers Institute for Medical Research, and the University of Oxford have developed an AI-based model called “RegVelo.” RegVelo not only tracks the developmental pathways of cells but also simulates how these pathways change.

Forscher am Helmholtz-Zentrum München, der Technischen Universität München (TUM), dem Stowers Institute for Medical Research und der Universität Oxford haben ein KI-basiertes Modell unter dem Namen „RegVelo" entwickelt. RegVelo kann nicht nur Entwicklungswege von Zellen nachverfolgen, sondern auch simulieren, wie sich diese Wege verändern.  

A team led by Prof. Gil Westmeyer, Director of the Institute for Synthetic Biomedicine (ISBM) at Helmholtz Munich, has developed a new method for repeatedly obtaining up-to-date genetic information from living cells without destroying them. This will in future enable better monitoring of stem cells for therapies or the effects of drugs within the cells.

In summer the EU will launch a call for proposals as part of its Innovation Health Initiative (IHI) funding program, under which European consortia comprising academia, industry, and public authorities can apply for funding to develop an AI-based model and framework to support the elimination of a second animal species in drug trials.

At the today's 55th Seminar on Laboratory Animals and Animal Testing at the Federal Institute for Risk Assessment, alternative approachesto the handling of laboratory animals were discussed. A consortium of various German research institutions is pursuing the goal of establishing a nationwide online platform to support the placement of laboratory animals in the future. 

London: LUSH Prize Winners Honored

Monday, 18 May 2026 14:27

This year, a group of interesting winners has once again been honored with the prestigious LUSH Prize. They shared the total prize of £250,000 across the categories of science, education, public awareness, advocacy, and early-career researchers.

Together with other partners, Professor Stefan Dübel and Professor Michael Hust, researchers at the Technical University of Braunschweig, have received the “Replication Prize” from the U.S. National Institutes of Health (NIH). The team was honored for its work, which improves the reproducibility of antibody experiments and avoids the use of animal testing.

A research team led by Dr. Margherita Yayio Turco from Friedrich Miescher Institute for Biomedical Research, based in Basel, has succeeded in replicating the menstrual cycle in vitro using organoids. The endometrial organoids can mimic the natural breakdown and regrowth of the uterine mucosa in response to hormones, making it possible to track how different cell types interact and regenerate tissue over time.