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A team of researchers from the Vienna University of Technology has developed a new hydrogel. It has an accessory molecule that can give cells a "marching direction" after irradiation with laser light. This allows microtissue structures, such as a blood vessel in an organoid - which is a tissue replica that is intended to replace animal testing - to be created specifically in the desired location.

In order to achieve a better assessment of environmental chemicals, the EU has launched the international partnership PARC - short for "European Partnership for the Assessment of Risk from Chemicals". It involves 199 research groups from 28 countries and three EU agencies. The aim is to close gaps in knowledge about the effects of chemicals, promote innovation and gradually eliminate animal testing.

The European Partnership for Alternatives to Animal Testing (EPAA) aims to promote the development, validation and acceptance of 3Rs alternative approaches (replacement, reduction and refinement of testing on animals). The 3Rs science prize is granted every two years to a scientist with an outstanding contribution to 3Rs. We want to promote positive contributions from industry or academia and encourage more scientists to focus their research on the 3Rs goals.

Together with her team, Dr. Cindrilla Chumduri, group leader at the Department of Microbiology at Julius-Maximilians-Universität Würzburg (JMU), has developed organoids of the female cervix.

Dr. Beate Krämer and Dr. Heike Behrensdorf-Nicol, scientists from the Department of Veterinary Medicine at the Paul Ehrlich Institute, have won the Research Prize of the State of Rhineland-Palatinate for their research on the "Relevance of the Irreversibility Test for Tetanus Toxoids".

PETA Science Consortium International e.V., the Physicians Committee for Responsible Medicine (PCRM), and the Alternatives Research and Development Foundation (ARDF) are offering grants for free catalogue recombinant antibodies for use in research and testing.

A team of researchers from the Natural and Medical Sciences Institute in Reutlingen (NMI), together with colleagues from the Medical Faculty of the Tübingen University as well as from the Fraunhofer Institute IGB, has developed an obesity model on a chip. The model is called Mix & Match and integrates all important cellular components that can also be found in human white adipose tissue.

A cell-based neuropathy disease model on-chip developed by Hesperos Inc. in Florida and colleagues is able to successfully recapitulate the neurophysiological features of two rare autoimmune demyelinating neuropathies. Additionally, it has been shown that the model is suitable for assessing the efficacy of new therapeutics.

Scientists at the Technical University of Berlin and colleagues have successfully developed an in vitro approach of a human neuroblastoma in a surrounding human cellular environment and treated it with drugs. They succeeded in treating the metastasis. At the same time, they were able to observe the influence on the surrounding tissue.

Prof. Doris Wilflingseder from the Medical University of Innsbruck and Prof. Peter Ertl from the Vienna University of Technology were honored with the Austrian State Prize for the Promotion of Alternative Methods to Animal Experiments 2021.