A team at Kyoto University has developed a human induced pluripotent stem cell-derived proximal tubule-on-chip (OPTECs-on-chip). It has the necessary functionality and polarity of important kidney transporters. According to the developers, the kidney chip model can therefore be used to assess drug transport and nephrotoxicity.
With the Hamburg Research Prize for Alternatives to Animal Testing, the the Hamburg Senate wants to actively support the development towards a future without animal testing, says Science Senator Katharina Fegebank (Bündnis 90/die Grünen) in the current press release. The prize was divided among three winners.
Every year, the BMEL announces an animal welfare research prize with a total prize money of 25,000 euros. However, everything is different this year: The prize has been redesigned. It will be awarded in three categories and the prize money amounts to a total of 220,000 euros. And there's something else that's different.
At the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, a three-dimensional model of human skin has been developed for the first time that precisely and quickly displays the skin's reaction to substances directly on living tissue.
A team of researchers at the Center for Applied Tissue Engineering and Regenerative Medicine (CANTER) at Munich University of Applied Sciences has succeeded in modifying a simple 3D printer so that it can create biological structures at the press of a button. This is an opportunity for small laboratories to conduct research in this area too.
For the 21st time, the European Congress on Alternatives to Animal Testing took place in Linz, and for the second time at the Medical Campus of Johannes Keppler University. Young scientists from 30 countries presented their findings and developments.
On October 18, 2024, the third 3R Symposium will take place at Saarland University. This time, the topic will be “Animal-free methods in pharmaceutical research”.
Researchers from the contract research company Hesperos Inc. as well as from the University of Central Florida (UCF) have developed a model with aged nerve cells of the human cerebral cortex to understand the role of senescence in Alzheimer's disease and to find treatment options for Alzheimer's disease.
The European Partnership for Alternatives to Animal Testing (EPAA) EPAA promotes the development, validation and acceptance of 3R alternative approaches (replacement, reduction and refinement of animal testing). Therefore, every two years the 3R Science Award is presented to a scientist who has made an outstanding contribution to the 3Rs. Contributions can come from industry or academia.
Several research associations in Germany have joined forces under the coordination of Prof. Dr. Bernhard Krämer from the University Women's Hospital in Tübingen to find new treatment options for endometriosis in the “ENDO-RELIEF” project.