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Medical devices for advanced therapies are gene therapies, somatic cell therapies, or the use of genetically modified tissues in cases where conventional therapies fail. Such medical devices must also be tested for safety and possible immune reactions in the same way as drugs or other medical devices.

This year's Saarland Prize for Alternative Methods to Animal Testing was awarded to Dr. Albert Omlor of Homburg University Hospital and Dr. Jennifer Herrmann of the Helmholtz Institute for Pharmaceutical Research.

The German Federal Ministry of Education and Research (BMBF) has issued the "Guideline for the Funding of Preclinical Confirmatory Studies and Systematic Reviews". In addition to necessary systematic reviews and meta-analyses on preclinical research topics, it is also possible to apply for funding to use scientifically recognized "alternative methods".

Applicants are invited to submit project proposals addressing missing key elements to implement New Approach Methodologies (NAMs, new non-animal method approaches) in EFSA's scientific assessment process. The aim is to use this to improve decision-making in the food and feed sectors.

A new survey conducted by the EU reveals gaps in knowledge about the animal-free production of serums, antibodies, and enzymes.  

An international consortium of researchers including the Max Delbrück Center (MDC) has summarized more than 7,200 largely unexplored gene segments that may encode new proteins. They are thought to have arisen phylogenetically late during primate evolution and therefore do not occur in other mammals such as mice.

Cerebral cortex in the Petri dish

Wednesday, 06 July 2022 13:21

A German-Israeli team of researchers has succeeded in recreating the outer human cerebral cortex in an organoid form in the petri dish. They have found a way to more easily grow a type of stem cell needed for this purpose.

The hDMT (human Organ and Disease Model Technologies) research consortium at Leiden University has inserted a functioning lymphatic vessel into an organ-on-a-chip system. This means that the technology of replicating human organs in miniature has now advanced a significant step further.

As the ninth State of the United States, Louisiana prohibits the marketing of cosmetics tested on animals. Previously, California, Nevada, Illinois, Virginia, Maryland, Maine, Hawaii, and New Jersey, have been convinced of new animal-free practices.

Citizens can still sign up for the EU Citizens' Initiative for an animal-free EU until August 31 of this year.