Monday, 01 April 2024 15:51

Bisphenols can impair important adrenal hormones Featured

In an in vitro study, the scientists Lydia Kürzinger and Benedikt Pötzl from the Department of Endocrinology and Diabetology at University Hospital Würzburg have investigated the effects of bisphenols on adrenal hormone synthesis. They made some interesting discoveries.

In cell culture experiments, the assistant doctor as well as the doctoral student were able to demonstrate the influence of bisphenol A (BPA), F (BPF) and S (BPS) on the secretion of 15 different adrenal hormones, whereby individual hormones were upregulated and others downregulated. Clinically relevant hormones such as cortisol, aldosterone and dehydroepiandrosterone were inhibited. They have an important function in the stress response, blood pressure control, sexual differentiation and puberty, according to a press release. Bisphenols are a group of chemical substances that are used in many plastics as plasticizers or stabilizers.

The research team is supported by the German Research Foundation and has received the Bruno Allolio Adrenal Prize 2024 in the amount of 8,000 euros for their research.

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