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Researchers from the Organo-Lab at the University of Tübingen, Germany, have developed an immuno-competent choroid on-chip model based on human cells. The model enables the study of drug-induced toxicity reactions in the eye or inflammatory diseases of the choroid such as uveitis and wet age-related macular degeneration.

An international team of researchers led by the University of Cambridge has discovered new findings on the development of Alzheimer's disease in a patient study.

A team of researchers led by the Paul Ehrlich Institute has studied the interaction between the Zika virus and the antiviral restriction factor tetherin.

Reproductive crisis in cancer research

Sunday, 09 January 2022 13:46

Eight years ago, the Reproducibility Project: Cancer Biology (RP: CB) was started. The goal was to replicate the results of top cancer laboratories. Looking at high-ranking research articles from 2010 and 2012, the team has now come to a sobering conclusion: The reproducibility of the work is less than 50%.

German researchers have found a particularly active form of immune cells in patients suffering from severe COVID-19. The so-called CD16-positive T cells have an increased cytotoxic effect, among other things on the inner cell layer of blood vessels. This could explain the severe courses of Covid-19.

Together, Republican and Democratic representatives have reintroduced the so-called Humane Cosmetics Act in the Senate. The bill would end the testing of cosmetic products on animals and ban the sale of products developed through animal testing throughout the United States.

Scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI), Würzburg, and the Helmholtz Centre for Infection Research (HZI), Braunschweig, have found an immune defense protein that can inhibit the proliferation of SARS-CoV-2 by a factor of 20.

Viral pathogens such as the coronavirus SARS-CoV-2 alter individual cell components but can provide information about how viral diseases develop. Scientists from the University of Heidelberg have found a new, powerful imaging technique: Soft X-ray Tomography (SXT). They used it to examine cell cultures from kidney and lung tissue infected with SARS-CoV-2.

Volunteer study: When the air gets thinner...

Wednesday, 08 December 2021 13:31

Researchers at the University of Duisburg Essen want to investigate how the human immune system reacts to oxygen deficiency and how inflammatory reactions are influenced. For this purpose, they are working with volunteers in an altitude training chamber.

A researcher team from the Department of Experimental Endocrinology at Charité Berlin, together with a researcher from the Federal Institute for Risk Assessment Berlin, has been awarded this year's prize for promoting research into replacement and supplementary methods for animal experiments in research and teaching by the state of Berlin.