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New ECVAM Status Report 2021 published

Thursday, 07 April 2022 17:41

The European validation authority EURL ECVAM has published its 2021 status report. It covers research, development, and validation activities in 2021, as well as initiatives that promote the adoption and use of non-animal methods and approaches in science and regulation.

Between April 18 and June 17 this year, applicants can nominate themselves or be nominated for the LUSH Prize 2022. The prize is worth a total of £250,000 and honors researchers and engaged individuals in five categories: Science, Training, Public Awareness, Lobbying, Young Researcher, and Political Achievement.  

The European Validation Authority EURL ECVAM is seeking members for its expert group ESAC (EURL ECVAM Scientific Advisory Committee) to advise the European Commission on issues related to non-animal methods.

Every year in the EU, nearly one million animals are used for antibody manufacturing and production, many of them are suffering from the mouse ascites method. This occurs although modern technologies exist that do not require the use of animals. Non-animal methods for generating and producing antibodies, such as phage display technology, have been available for years.

There was already evidence that coronaviruses can enter the retina of the eye and cause damage. Therefore, scientists from the Max Planck Institute for Molecular Biomedicine and the Westfälische Wilhelms-Universität Münster have investigated the consequences of a SARS-Cov-2 infection with specially developed retinal organoids.

DNTOX, a spin-off of the Leibniz Institute for Environmental Medicine Research, Düsseldorf, was awarded as one of the best business concepts in 2022 in the Science4Life business competition.

Scientists at the Institute of Stem Cell Research and Regenerative Medicine at the University Hospital Düsseldorf have developed an in vitro model of acute kidney injury by treating specially developed three-dimensional kidney organoids with a nephrotoxic substance.

In order to develop alternative methods in as many areas as possible where animal experiments are carried out, again, the German Federal Ministry of Food and Agriculture (BMEL) is inviting applicants for this year's animal protection research prize.

Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University succeeded in culturing human B and T cells in a microfluidic organ chip device and getting them to spontaneously form functional lymphoid follicles. These are normally found in the lymph node and other parts of the human body and mediate immune responses.

The Center for Alternatives to Animal Testing at Johns Hopkins University, Baltimore (CAAT) calls for Alan and Helene Goldberg in vitro toxicology grants. The support period is 2023-2024.