The stability of DyNAtrix's DNA crosslinks enables controlled adjustment of stress-relaxation properties, mimicking the properties of living tissue. DyNAtrix is self-healing and suitable for 3D printing. The matrix can be degraded in a controlled manner using enzymes.
The work was published in Nature Nanotechnology:
Peng, YH., Hsiao, S.K., Gupta, K. et al. Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture. Nat. Nanotechnol. (2023). https://doi.org/10.1038/s41565-023-01483-3
More information:
https://www.ipfdd.de/en/communication/news/news-detail/newsitem/1818/
https://www.ipfdd.de/de/forschung/institute-of-biofunctional-polymer-materials/team/dr-elisha-krieg/