Working group - a Portrait (15)

InVitro+Jobs presents scientists and their innovative research in a regular feature called “Working Group – a Portrait”. We focus on newly developed methods, their evaluation and their potential for reducing and where possible replacing animal experimentation according to the 3R principles of Russel & Burch (reduce, refine, replace).

 

Working group – a Portrait:
IfADo – Leibniz Research Centre for Working Environment and Human Factors,
Department of Toxicology, Research Group Systems Toxicology


The IfADo – Leibniz Research Centre for Working Environment and Human Factors in Dortmund is a research institute, where scientists investigate the growing challenges in the working environment in the face of an increasingly ageing population (ergonomics), regarding the part played by the immune system with regard to infections and cancer (immunology), the part played by the cerebral cortex and neuroplasticity in experiencing, behaviour, learning and memory formation (psychology and neurosciences), and with toxicology, investigating the toxic processes caused by chemicals in the liver or the nervous system (1).

InVitro+Jobs presents scientists and their innovative research in a regular feature called “Working Group – a Portrait”. We focus on newly developed methods, their evaluation and their potential for reducing and where possible replacing animal experimentation according to the 3R principles of Russel & Burch (reduce, refine, replace).

In this feature we present an institute that amongst other things researches the development of in vitro disease models (“diseases in a dish”). The models allow to study of disease developments based on patient-specific human cells instead on genetic modified animals (animal models).

InVitro+Jobs presents scientists and their innovative research in a regular feature called “Working Group – a Portrait”. We focus on newly developed methods, their evaluation and their potential for reducing and where possible replacing animal experimentation according to the 3R principles of Russel & Burch (reduce, refine, replace). In this edition we feature important research conducted by Prof. Dr. Gerhard Gstraunthaler, head of the working group „Renal Molecular Physiology “at the Medical University of Innsbruck.

InVitro+Jobs presents scientists and their innovative research in a regular feature called “Working Group – a Portrait”. We focus on newly developed methods, their evaluation and their potential for reducing and where possible replacing animal experimentation according to the 3R principles of Russel & Burch (reduce, refine, replace).


Working Group ‒ a Portrait: TissUse GmbH


This issue deals with highly topical research into and the development of minute organ-like cellular structures on a microchip, known as a “multi-organ chip”. The goal is use these platforms in order to replace substance testing on animals. Here we introduce the company TissUse.

InVitroJobs presents scientists and their innovative research in a regular feature called “Working Group – a Portrait”. We focus on newly developed methods, their evaluation and their potential for reducing and where possible replacing animal experimentation according to the 3R principles of Russel & Burch (reduce, refine, replace).

In this article we present an institute that researches the retention of organic substances in the environment and their evaluation. Head of the institute is the chemist Prof. Dr. Klaus Kümmerer. His research foci are sustainable chemistry, material resources and trace elements in the aquatic environment. Prof. Kümmerer looks for new properties for pharmaceuticals, with the goal of making them degradable in rivers and lakes. To this end the institute employs computer-based methods. A staff member also has the task of modelling and evaluating the global dispersion of harmful substances.

Working Group – a Portrait: ACTO e.V.

Wednesday, 23 July 2014 13:16

InVitroJobs presents scientists and their innovative research in a regular feature called “Working Group – a Portrait”. We focus on newly developed methods, their evaluation and their potential for reducing and where possible replacing animal experimentation according to the 3R principles of Russel & Burch (reduce, refine, replace).

In our current portrait we present the Aachen Centrum of Technology Transfer in Ophthalmology (ACTO). We describe a particular method of ACTO, the Ex Vivo Eye Irritation Test (EVEIT). The method provides - similar to the Bovine Corneal Opacity / Permeability Assay (BCOP) - an animal-free alternative to the Draize eye irritation test on living rabbits.

Working Group – a Portrait: Medicyte GmbH

Tuesday, 05 November 2013 18:18

InVitroJobs regularly presents scientists and their innovative research in “Working group – a Portrait”. The focus is on newly developed methods, their evaluation and an outlook on which animal experiments can be reduced, refined or preferably replaced according to the 3R principle. In this instalment we present the Medicyte GmbH in Heidelberg, Germany, a company that develops special cell lines for use in animal-free research.

InVitroJobs presents scientists and their innovative research in a regular feature called “Working Group – a Portrait”. We will focus on newly developed methods, their evaluation and their potential for reducing and where possible replacing animal experimentation according to the 3R principles of Russel & Burch (reduce, refine, replace). In this issue, we present PharmaInformatic from Emden, Germany.

Working Group – a Portrait: Across Barriers

Thursday, 04 October 2012 21:52

InvitroJobs presents scientists and their innovative research in a regular feature called “Working Group – a Portrait”. We will focus on newly developed methods, their evaluation and their potential for reducing and where possible replacing animal experimentation according to the 3R principles of Russel & Burch (reduce, refine, replace). In this issue, we present Across Barriers from Saarbrücken.

InvitroJobs presents scientists and their innovative research in a regular feature called “Working Group – a Portrait”. We will focus on newly developed methods, their evaluation and their potential for reducing and where possible replacing animal experimentation according to the 3R principles of Russel & Burch (reduce, refine, replace).
In this issue we introduce the work group “Environmental Toxicological Risk Assessment and Human Sphere Models”, at the Leibniz Research Institute for Environmental Medicine (IUF), Heinrich Heine University Düsseldorf.

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