The water research institute EAWAG has developed a new method using a gill cell line (RTgill-W1) of rainbow trout to replace acute toxicity tests with fish (ecotoxicity tests). This in vitro test can be used to test sewage water, chemicals, pesticides, biocides and pharmaceuticals for their impact on the aquatic environment. The test is already internationally certified according to ISO, but not yet OECD approved.
Now it is planned to further optimize this test by using the animal-free media without fetal calf serum for the cultivation of the cells.
Eawag researcher Prof. Kristin Schirmer is receiving around 251,000 Swiss francs for her project. She would like to offer her already ISO-certified toxicity test with fish cells completely without animal experiments.
Source:
https://www.eawag.ch/de/news-agenda/news-plattform/
https://www.dora.lib4ri.ch/eawag/islandora/object/eawag%3A11724/datastream/PDF/view
https://www.eawag.ch/de/news-agenda/news-plattform/news/news/