Friday, 05 July 2019 09:41

Fish gill cell test receives project funding Featured

The 3R Competence Center Switzerland (3RCC) supports six projects with a total of CHF 1.2 millions to promote the 3Rs principle (replacement, reduction and refinement of animal experiments). Among the funded projects is the EAWAG fish cell test.


The water research institute EAWAG has developed a new method using a gill cell line (RTgill-W1) of rainbow trout to replace acute toxicity tests with fish (ecotoxicity tests). This in vitro test can be used to test sewage water, chemicals, pesticides, biocides and pharmaceuticals for their impact on the aquatic environment. The test is already internationally certified according to ISO, but not yet OECD approved.

Now it is planned to further optimize this test by using the animal-free media without fetal calf serum for the cultivation of the cells.

Eawag researcher Prof. Kristin Schirmer is receiving around 251,000 Swiss francs for her project. She would like to offer her already ISO-certified toxicity test with fish cells completely without animal experiments.

Source:
https://www.eawag.ch/de/news-agenda/news-plattform/
https://www.dora.lib4ri.ch/eawag/islandora/object/eawag%3A11724/datastream/PDF/view
https://www.eawag.ch/de/news-agenda/news-plattform/news/news/