Searching for genes, that were linked to the angiotensin I converting enzyme 2 (ACE2) they found several genes highly significantly correlating, like the transmembrane serine protease 4 (TMPRSS4) as well as, among others, those that have to do with the viral life cycle and evoke the interferon response to the virus. The data set obtained can contribute to a better understanding of the molecular mechanisms underlying COVID-19.
Original publication:
Wasco Wruck & James Adjaye (2020). A meta-analysis of transcriptomes of SARS-Cov2 infected human lung epithelial cells identifies transmembrane serine proteases co-expressed with ACE2 and biological processes related to viral entry, immunity, inflammation and cellular stress.
Source:
https://www.biorxiv.org/content/10.1101/2020.05.12.091314v1.full.pdf