Tuesday, 06 February 2024 12:35

Freiburg: Funding for non-animal safety assessment of cancer therapies Featured

Scientists from the Institute of Transfusion Medicine and Gene Therapy at Freiburg University Medical Center, led by Prof. Toni Cathomen, have received funding of around €1.17 million as part of the British "Crack it" Challenge. The team is researching an innovative, animal-free approach to the safety assessment of modern cancer therapies.

This involves so-called CAR-T cell therapies, in which the body's own immune cells (T cells) are modified to enable them to recognize and fight cancer cells in a targeted manner. However, the side effects and complications of these methods need to be researched, which has so far been done on animals. Prof. Cathomen and his team are developing disease models and cell therapies based on induced pluripotent stem cells (iPS cells).

for more information:
https://www.uniklinik-freiburg.de/presse/pressemitteilungen/detailansicht/4095-eine-million-euro-fuer-tierfreie-krebsforschung.html
https://www.med.uni-freiburg.de/de/fakultaet/profs/cathomen
Wolf P, Alzubi J, Gratzke C, Cathomen T. Das Potenzial der CAR-T-Zelltherapie für Prostatakrebs. Nat Rev Urol. 2021 Sep;18(9):556-571. Doi: 10.1038/s41585-021-00488-8. Epub 2021 8. Juli PMID: 34239139. https://pubmed.ncbi.nlm.nih.gov/34239139/