The results should help to gain insights into dilated cardiomyopathy (DCM) and the hypertrophic cardiomyopathy (HCM) as well as develop new therapies against cardiac insufficiency.
For the implementation of the project, the British project partners are providing human heart samples from healthy and diseased donors. The Hamburg team under the leadership of by Prof. Thomas Eschenhagen cultivates heart tissue in the laboratory. With in vitro disease models heart diseases can be simulated and pharmacological drug tests can be performed. Computer modelling is also part of the project.
The project is funded by the German Centre for Cardiovascular Research, DZHK, and the British Heart Foundation with a total of 2.5 million euros for three years. It is coordinated by the Max Delbrück Center in Berlin.
Source and more information:
https://www.mdc-berlin.de/news/press/unlocking-secrets-heart-cells
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Friday, 26 April 2019 13:38
At the molecular level against cardiac insufficiency Featured
In the project "Spatially resolved cellular and molecular drivers of cardiac remodeling in healthy and failing", a British-German team of researchers wants to analyze thousands of individual cells from different areas of the heart with the most modern methods to understand the heart at a molecular level.
Dr. rer. nat.
Menschen für Tierrechte - Tierversuchsgegner Rheinland-Pfalz e.V.