So far, dogs, especially beagle, are routinely poisoned in Japan and South Korea. In the process, the animals receive one dose of the test agent, which is administered daily for a period of one year. Thereafter, the animals are killed in order to investigate its organs.
These controversial tests have been criticised for a long time because the results do not lead to any additional information, which go beyond what has already been learned from other tests that are relevant to human safety. For that reason it can be abolished.
In the USA, the EU, India, Brazil, Canada, Australia and China, these long-term testing on dogs is no longer carried out routinely.
Source:
http://www.hsi.org/news/press_releases/2017/10/report-pesticide-testing-japan-101817. html