NOTOX brings together eleven internationally renowned and interdisciplinary research teams from all over Europe, including academic research laboratories and four small and medium sized enterprises (SMEs).

The liver is the central organ for the elimination of toxic substances in the human body. Therefore NOTOX scientists closely examine in test-tube experiments how such substances affect human liver cells in the long run. The processes and reactions they observe in the cells are being translated into highly complex computer models. The overall goal is to develop algorithms that closely mimic the processes which actually take place in human tissues when exposed to toxic substances.

These computational models will allow for reliable long-term predictions and thus help to replace animal testing in the long run.

NOTOX has posted a film which give a good overview about the scientific work of that European research cluster (see http://www.notox-sb.eu/film).

For more information:
http://www.notox-sb.eu

Further information on the project, please contact the project Coordinator:
Prof. Elmar Heinzle
Universität des Saarlandes
Technische Biochemie
Gebäude A 1.5
66123 Saarbrücken
Tel: +49 681 302 2905
e.heinzle[at}mx.uni-saarland.de