The focus of his research is the tailor-made transport of drugs through biological barriers (skin, lungs and gastrointestinal system of the body) towards its site of action.
Together with his team at the Saarbrücken HIPS, a joint institution of the Helmholtz Centre for Infection Research (HZI) in Braunschweig and the University of the Saarland he developes effective delivery systems in nanoparticle form. These tiny particles (ranging in size of up to 100 nanometers) keep together the pharmaceutically active substances during transport through the barriers. The drug to be released only at the desired site of action after the nanocarrier have been decomposed.
The Research on the functioning of these carrier systems is done in vitro in bioreactors with human tissue cultures - which means without the use of animals. InVitroJobs reported several times (1, 2, 3, 4) .
http://www.invitrojobs.de/index.php/en/aktuelles-archiv/345-saarbruecken-nano-wirkstoff-faehre-soll-biologische-barriere-austricksen.html
http://www.invitrojobs.de/index.php/en/aktuelles-archiv/204-helmholtz-kooperation-alveolarzell-modell-mit-konstanten-zelleigenschaften.html
http://www.invitrojobs.de/index.php/en/aktuelles-archiv/190-qdas-tier-in-seiner-komplexitaet-ist-eine-blackboxq.html
http://www.invitrojobs.de/index.php/en/aktuelles-archiv/175-interview-mit-tierschutzforschungspreistraeger-rheinland-pfalz.html
Source:
http://www.process.vogel.de/pharma/articles/489913/
https://themedicinemaker.com/the-power-list-2015/