News
In vitro: Researchers show strong inhibition of interferon-1 defence by coronavirus protein
Wednesday, 27 May 2020 08:52Using cell cultures, a team of scientists from the Universities of Tokyo, Hiroshima, Kyoto, as well as from Kanagawa has found out, that the Sars-Cov2 protein ORF3b inhibits the innate immune defense by INF1 even more strongly than other coronaviruses previously investigated.
ECVAM recommends non-animal antibody production
Thursday, 21 May 2020 16:59The JRC's EU reference laboratory for alternatives to animal testing (EURL ECVAM) has made a recommendation urging end-users and other stakeholders to recognize the scientific validity of non-animal-derived antibodies and to stop using animals for the development and production of antibodies.
E-Morph-Assay for the investigation of endocrine disrupting substances
Thursday, 21 May 2020 11:56Scientists at the Federal Institute for Risk Assessment in Berlin have developed a test based on a human cell line with which chemicals can be tested for their hormone activity.
Using bioinformatics for Covid-19 clarification
Thursday, 14 May 2020 10:25Prof. James Adjaye, head of the Institute for Stem Cell Research and Regenerative Medicine in Düsseldorf, and the bioinformatician Wasco Wruck have carried out a meta-analysis of RNA sequence data from three Sars-Cov2 studies, in which human lung epithelial cells had been used.
New Working group – a Portrait: Dynamic42 GmbH
Thursday, 14 May 2020 07:51InVitro+Jobs presents scientists and their innovative research in a regular feature called “Working Group – a Portrait”. We focus on newly developed methods, their evaluation, and their potential for reducing and where possible replacing animal experimentation according to the 3R principles of Russel & Burch (reduce, refine, replace). In this issue, we present a young spin-off from Jena, Dynamic42 GmbH.
MIT: Physiom-on-a-Chip model developed
Wednesday, 13 May 2020 21:49Bioengineers from the laboratory of the Massachusetts Institute of Technology in Cambridge, have developed a multi-tissue model to study the relationships between organs and the immune system.
Immune cells discovered in the mammary gland
Thursday, 30 April 2020 23:19Australian breast cancer researchers have discovered a new type of immune cells in the human breast gland, called ductus macrophages. These cells could play an important role in the fight against breast cancer.
3Rs Science Prize 2020: Call for submissions
Wednesday, 29 April 2020 09:07The European Partnership for Alternatives Approaches to Animal Testing (EPAA) aims to promote the development, validation and acceptance of 3Rs alternative approaches (replacement, reduction and refinement of testing on animals). The 3Rs science prize is granted every two years to a scientist with an outstanding contribution to the 3Rs.
Infection Research with Alveolar Organoids
Wednesday, 22 April 2020 14:52Scientists at the Max Planck Institute for Infection Biology in Berlin led by Prof. Thomas F. Meyer, in cooperation with Prof. Andreas Hocke from the Charité University Hospital in Berlin, have developed an in vitro model of the human lung epithelium in 2018, that can currently be used for drug research against the coronavirus Sars-CoV-2.
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