The European Reference Laboratory for alternatives to animal testing (EURL-ECVAM) has launched a validation study evaluating in vitro methods that are able to detect endocrine disruptive chemicals. In the validation study, 17 different in vitro methods are considered as candidates.

The American Institute for In Vitro Sciences (IIVS) has currently opened a laboratory for in vitro respiration studies. To start inhalation toxicology studies, IIVS received a in vitro exposure system. With the new device, the scientists want to investigate the effects of new cigarette products, such as the next generation heat-not-burn systems and e-cigarettes on human lung cells.

In a consultation paper on a reform of the Australian Chemicals Directive (National Industrial Chemicals Notification and Assessment Scheme, NICNAS) the Health Department of the Australian Government provides a ban for the production and marketing of "cosmetic chemicals" tested on animals in Australia from the first of July 2018 onwards. Cosmetic chemicals are those which are used solely for cosmetic purposes.

Animal-Free Research UK (formerly Dr. Hadwen Trust), the largest British foundation for animal-free medical research has invested 3.2 million pounds in research during the past 5 years and compiled a database of commercially available serum-free media, available as a resource for researchers around the world looking for suitable media. Goal is to replace the fetal calf sera as quick as possible. Together with the 3R-Centre Utrecht Life Sciences the database will be launched with a short opening ceremony in Utrecht.