Within the project ReProTect - a project within the 6th European Framework Program - a ring trial, named the “Feasibility Study”, was conducted in which 10 chemicals, whose toxic effects on reproduction are already well-documented from animal experiments, have been tested in a blinded study. The researchers developed a completely new approach. Instead of relying on a single test, they used a test battery of 14 in vitro assays. This approach allowed a robust prediction of adverse effects on fertility and embryonic development of the test chemicals in vivo.
Original article:
B. Schenk et al. (2010): The ReProTect Feasibility Study, a novel comprehensive in vitro approach to detect reproductive toxicants. In: Reproductive Toxicology 30 (2010), S. 200–218. doi:10.1016/j.reprotox.2010.05.012
Additional information on this topic: Animal experiments for the European Union Regulation (EC) No 1907/2006 of 18 December 2006 for Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), in force on 01 June 2007, startet in Europe in 2010.
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Thursday, 12 August 2010 14:31
Hurtful effects of chemicals on reproduction determined reliably with in vitro "test battery" Featured
A group of researchers, funded by the European Comission, published in the actual issue of „Reproductive Toxicology“ a study, the so called "Feasibility Study" within the project ReProTect, in which they determine the hurtful effects of chemicals on reproduction reliably with animal-free methods.
Dr. rer. nat.
Menschen für Tierrechte - Tierversuchsgegner Rheinland-Pfalz e.V.