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Monday, 02 June 2025 19:23

Organ models with blood vessels on a chip Featured

Scientists at the Vienna University of Technology (TU Wien) together with Keio University in Japan have developed a new method for creating blood vessels in tiny organ models on a chip - using ultrashort laser pulses.


The scientists, led by Prof. Aleksandr Ovsianikov from the Institute of Materials Science and Technology at TU Wien, can use this method to create channels in tiny organ models that are only 100 micrometers apart from each other. The artificial blood vessels can be colonized with endothelial cells that react in the same way as the body's own endothelial cells and also respond to inflammatory processes as in the body.

Original publication:
Salvadori A, Watanabe M, Markovic M, Sudo R, Ovsianikov A. (2025). Controlled microvasculature for organ-on-a-chip applications produced by high-definition laser patterning. Biofabrication, May 27;17(3). doi: 10.1088/1758-5090/add37e. PMID: 40315895.

Further information:
https://www.tuwien.at/tu-wien/aktuelles/news/news/ein-chip-mit-natuerlichen-blutgefaessen


 

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