For their investigations, the research team led by Prof. Eberhard Hildt of the PEI isolated exosomes from the cell culture supernatant of HBV-producing human liver cells. These provided evidence of hepatitis B viruses. After the dissolution of the exosomes' membrane, intact HBV viruses were released outside the cells.
The finding was published online in the journal Cellular and Molecular Gastroenterology and Hepatology:
Wu Q, Glitscher M, Tonneacher S, Schollmeier A, Raupach J, Zahn T, Eberle R, Krijnse-Locker J, Basic M, Hildt E (2022): Presence of intact hepatitis B virions in exosomes. Cell Mol Gastroenterol Hepatol, Sep 29, https://www.cmghjournal.org/article/S2352-345X(22)00207-7/fulltext.