Under the FDA Modernization Act of 2021, an applicant for marketing approval of a new drug may use methods other than animal testing to demonstrate the drug's safety and effectiveness, see https://www.congress.gov/bill/117th-congress/house-bill/2565
Hopes now rest on a similar process in the U.S. Senate in the coming months.
This represents the next major step toward phasing out animal testing, following the U.S. Environmental Protection Agency's 2020 work plan to gradually reduce animal testing for chemical risk assessment.
More information:
https://www.userwalls.news/n/house-passes-legislation-end-fda-animal-testing-mandate-3342184/