Wednesday, 15 January 2020 14:09

Paul Ehrlich Institute: Important findings on HIV with stem cells Featured

A research team headed by the Paul Ehrlich Institute in Langen, Germany, has generated induced pluripotent stem cells (iPSC) from a healthy person and two people with rare monogenetic diseases. By comparing the cells between healthy and sick people, it is possible to gain important insights into the processes involved in diseases and the immune response against HIV.


Scientists of the Paul Ehrlich Institute have worked together with colleagues from the Medical University of Hannover and from France to develop induced pluripotent stem cells (iPSCs) of a healthy person, a patient with Aicardi-Goutières syndrome as well as from a patient with Renpenning syndrome. In these diseases, proteins play a role that is also important for the immunological recognition of the human immunodeficiency virus (HIV). With iPSCs and derived cell types, new insights into the syndromes and the human immune system in the fight against HIV can be won.

The journal Stem Cell Research reports on the results of this research in three articles, published in the December 2019 and January 2020.

Further information:
https://www.pei.de/DE/newsroom/pm/jahr/2020/02-pluripotente-stammzellen-erforschung-hiv.html