Friday, 22 March 2019 14:16

USA: Organ-on-a-chip models for clarifying the opioid crisis Featured

Scientist at the National Center for Translational Science (NCATS) at the NIH in Washington, D. C., want to use organ-on-a-chip systems of the start-up company Hesperos to identify the causes of the national opioid crisis.


A demonstration of organ-on-a-chip technology using heart cells as an example, that have shown the effects of adrenaline on the human heart, has convinced authorities, physicians and scientists that the new technology is very helpful for investigations of drug side effects in the current opiodide crisis in the USA.

Every day, 130 people die in the USA from an overdose of opioid, and many more develop permanent medical problems and addiction. The NIH has made a combating this problem a priority and is therefore looking for new human-specific examination methods. Not only because of ethical reasons animal models are not suitable but above all because of scientific reasons due to differences in metabolism. Researchers often complain about the lack of transferability to the human situation.

Therefore they haven chosen the Human-on-a-Chip model of Hesperos in order to help in coping with this crisis with reliable causal research and data in the near future.

Source and further information:
https://www.hesperosinc.com/news/2019/3/18/hesperos-models-under-consideration-to-address-opiod-crisis