A variety of factors contribute to complex diseases and can be measured using "omics" methods. Databases such as VMH facilitate data interpretation for the underlying mechanisms.

The VMH includes 5,180 different metabolites, 17,730 different reactions, 3,695 human genes, 255 Mendelian diseases, 818 microbes, 632,685 microbial genes and 8,790 foods. It summarizes the current knowledge about human metabolism, divided into five interconnected resources "Human Metabolism", "Intestinal Microbiome", "Disease", "Nutrition" and "ReconMaps".

The VMH represents an interdisciplinary data base for data interpretation and hypothesis generation for the Biomedicine.

Services of the VMH are:
1. the provision of metabolic reconstructions of human and intestinal microbes suitable for metabolic modelling;
2. seven human metabolic mappings for data visualization;
3. a nutrition designer;
4. a user-friendly website and an application programming interface for accessing its contents;
5. user feedback option for community engagement
6. the connection of the units with 57 other web resources.

Original publication:
Alberto Noronha, Jennifer Modamio, Yohan Jarosz, Elisabeth Guerard, Nicolas Sompairac, German Preciat, Anna Dröfn Daníelsdóttir, Max Krecke, Diane Merten, Hulda S. Haraldsdóttir, Almut Heinken, Laurent Heirendt, Stefanía Magnúsdóttir, Dmitry A. Ravcheev, Swagatika Sahoo, Piotr Gawron, Lucia Friscioni, Beatriz Garcia, Mabel Prendergast, Alberto Puente, Mariana Rodrigues, Akansha Roy, Mouss Rouquaya, Luca Wiltgen, Alise Zagare, Elisabeth John, Maren Krueger, Inna Kuperstein, Andrei Zinovyev, Reinhard Schneider, Ronan M. T. Fleming & Ines Thiele (2019). The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease. Nucleic Acids Research 47, Database Issue D614-624. https://www.ncbi.nlm.nih.gov/pubmed/30371894

The VMH database can be found here: https://www.vmh.life/

Source:
https://www.vph-institute.org/news/the-virtual-metabolic-human-database.html