Thursday, 21 September 2017 11:30

3D printing of thick vascularized tissue constructs for tissue engineering and regenerative medicine Featured

Multidisciplinary research at the Wyss Institute has led to the development of a multi-material 3D bioprinting method that generates vascularized tissues composed of living human cells that are nearly ten-fold thicker than previously engineered tissues and that can sustain their architecture and function for upwards of six weeks.

3D bioprinting method to build a thick vascularized tissue structure comprising human stem cells, collective matrix, and blood vessel endothelial cells. The resulting soft tissue structure can be immediately perfused with nutrients as well as growth and differentiation factors.

This innovative bioprinting approach can be modified to create various vascularized 3D tissues for regenerative medicine and drug testing endeavors.

Read more here and watch the video:
https://wyss.harvard.edu/technology/3d-bioprinting/

* Roger A. Rowe, Kenneth M. Pryse, Clara F. Asnes, Elliot L. Elson & Guy M. Genin (2015): Collective Matrix Remodeling by Isolated Cells: Unionizing Home Improvement Do-It-Yourselfers. Biophys J. 108 (11): 2611–2612. doi: 10.1016/j.bpj.2015.04.026.