The funding will be used to develop three-dimensional microphysiological lab-on-a-chip platforms that will be able to mimic various human diseases. In the platforms living cells and human tissues to reproduce the biological functions of human organs and offer a new way to test the efficacy of pharmaceuticals.
The 15 million dollars in funding per year are initially planned for the first phase of a five-year project.
13 research groups are supported, which focus on microfluidic systems which, replicate renal diseases, tuberous sclerosis, children's hereditary diseases, salivary glands, congenital cardiomyopathies, atrial heart disease,
ovarian cysts, inflammatory complications during diabetes, vascular malformations, ALS and Parkinson's disease as well as lung diseases on the chip.
More information:
www.nih.gov/news-events/news-releases/nih-awards-15-million-support-development-3-d-human-tissue-models
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Wednesday, 20 September 2017 13:05
NIH supports translational in vitro research with USD 15 million Featured
More than 60 percent of investigational drugs fail in human clinical trials due to a lack of effectiveness, despite promising pre-clinical studies using cell and animal research models. For this resason, the National Institutes of Health (NIH) are now promoting 13 research projects that have failed to prove effective. The has approved a two-year funding programme totalling $ 15 million per year.
Dr. rer. nat.
Menschen für Tierrechte - Tierversuchsgegner Rheinland-Pfalz e.V.