PEPPER
The Pepper public private Platform is located in Paris. It is a non-profit association whose work started in 2020. It operates the validation of bioassays intending to identify endocrine disruptive (ED) properties of chemicals. ED is a key topic and authorities and industry need solid methods to implement many regulations and since last year, and classification in the renewed CLP (Classification, Labelling and Packaging) regulation. It both organizes and contributes to the funding of the validation operations for toxicology and ecotoxicology testing, with a view to conduct such methods to an international recognition such as the one provided by OECD Test Guidelines.
To date, Pepper is working on the validation of 11 methods, with two challenges: increasing, as expected by many international organisations, the efficiency of the validation management; ending the first series of validations.
The tasks in Pepper are:
* Identification and Readiness Assessment of candidate methods.
* Design of the validation experiments (how many substances, how many labs, planning steps…), issue of a call for participating laboratories, gathering expertise (“validation management group”), selection of contractors (data management, statistics… substance selection and preparation).
* Follow up and management of the process, including evolutions in the experimental procedure, reporting conclusions to the Pepper Scientific Council.
* Proposal of the method to international institutions, drafting of a validation report conduction of the process to an end.
A project Manager is devoted to each method.
The Validation Project Manager
Pepper is a team of 6 people with a high level of expertise, including a Director and a Chief Scientific Office.
You are working within this team with a close relationship with other members.
As Validation Project Manager, you will be responsible for all operations after a method has been selected
for validation in Pepper, up to and including the approval of the conclusions by the Scientific Council. To do
this, you are supervised by the CSO for the scientific aspects and by the Director for contractual matters. For
each method, two Pepper staff work closely together to ensure continuity. You are the leader for some
methods and the assistant for others.
You participate in the activities at the heart of Pepper’s mission, such as identifying and documenting the
test methods prior to selection and building up a proposal for international institutions.
You are involved in timetable to ensure to deliver validation results according the planning.
Your role also implies developing strong relationships with Pepper’s governance, with stakeholders, with the
Research field where these methods are being developed and with national, European and international
organisations in charge of validation (OECD, ISO…).
Profile
With an engineering degree or doctorate in biology, pharmacy or (eco)toxicology, you will have knowledge of endocrine disruption.
You will have a minimum of 5 years' experience, including solid practical experience of in vitro scientific experiments.
Experience in GLP laboratories and a good knowledge of the overall validation process would be an advantage.
Project management skills are a must.
Data management skills would be appreciated.
Fluency in English is essential. French is a plus.
Please send your CV with a covering letter stating your salary expectations to Philippe HUBERT CEO of
Pepper. This email address is being protected from spambots. You need JavaScript enabled to view it.
Answers are expected by July 15.
22 rue Charcot - 75013 PARIS France – Tel : +33 6 13 28 33