Wednesday, 03 February 2021 18:31

PhD candidate (m/f/d) Featured

  • Title: PhD candidate (m/f/d)
  • Type: Part-Time
  • Field of research: Toxicology/Cosmetics
  • Company name: Osnabrück University, Faculty of Human Sciences, Institute of Health Research and Education, Department of Biomedical Sciences
  • Address: Barbarastr. 22c/ 93
  • Zipcode: 49076
  • City: Osnabrück
  • Country: Germany
  • Company Website:
  • Contact person: Prof. Dr. Nicole Teusch
  • Contact email: nicole.teusch[at]
  • Description:

    The Department of Biomedical Sciences at the Institute of Health Research and Education, Faculty of Human Sciences, is looking for a

    PhD candidate (m/f/d)
    (Pay Scale 13 TV-L, 50 %)

    temporary for a period of three years.

    Your Duties:

    • Establishment and validation of an immunocompetent human three-dimensional full-thickness skin model in scientific collaboration with a research team consisting of partners from industry and academia.
    • Molecular differentiation of human immune cell lines or primary immune cells into Langerhans cell surrogates
    • In-depth characterization of Langerhans cell surrogates based on specific surface antigens by flow cytometry, confocal fluorescence microscopy and by molecular biological (e.g. quantitative real-time PCR, transcriptome analyses) and biochemical analyses (e.g. ELISA)
    • Development of cell culture conditions under which surrogates of Langerhans cells as central initiator cells of an immune reaction can be functionally integrated together with fibroblasts and keratinocytes in the tissue of the skin model in order to be able to map molecular mechanisms of skin sensitization in the 3D skin model and to inhibit this sensitization reaction in the presence of new active drug candidates.
    • Participation in Research while working towards a PhD


  • Qualifications:


    • A completed, outstanding scientific university degree (M.Sc. or diploma) in biology, molecular biomedicine, biochemistry or a related field.
    • Practical experience in cell biology, biochemistry and molecular biology laboratory methods
    • Above-average motivation to contribute to an interdisciplinary team in a proactive, goal-oriented and collegial manner
    • Structured approach to work and efficient work attitude
    • Very good command of written and spoken English
    • Willingness to face qualitatively and quantitatively high work demands


  • How to apply:

    Osnabrück University is a family-friendly university and is committed to helping working/studying parents balance their family and working lives.

    Osnabrück University seeks to guarantee equality of opportunity for women and men and strives to correct any gender imbalance in its schools and departments. If two candidates are equally qualified, preference will be given to the candidate with disability status.

    Please send your complete application documents in electronic form only (as one file in PDF format) to the office of the Institute for Health Research and Education at bewerbungigb[at] with the subject "NwF-BMG 2" by February 18, 2021.

    For further information regarding this vacancy, please contact Prof. Dr. Nicole Teusch at nicole.teusch[at]

  • Application deadline (date of receipt): Thursday, 18 February 2021
  • Vacancies: 1