The Hebrew University in Jerusalem, headed by Prof. Michal Goldberg and Prof. Nissim Benvenisty together with researchers from Heinrich Heine University in Dusseldorf, headed by Prof. James Adjaye, have uncovered a signalling pathway mechanism which is responsible for the formation of microcephaly. This disease picture is one of several that may occur in the genetic Nijmegen breakage syndrome (NBS).

Basic researchers from Excellenzcluster CNMPB in Göttingen led by Prof. Gerhard Braus use yeast cells to study cellular mechanisms of Morbus Parkinson. They got new insights about pathogenic processes.

To investigate heart rhythm disturbances in vitro, researchers led by Dr. Daniel Sinnecker from the Technical University of Munich have integrated an optical sensor in heart cells in order to distinguish heart cell types by their electric potential from each other. The heart cells are produced from patients´ induced pluripotent stem cells.

The updated guide on How to use and report (Q)SARs, published in July in English, has been translated to 22 EU languages. It provides an overview of the important aspects to consider when predicting properties of substances using (Q)SAR models and gives useful examples of good prediction practices.

From 24 to 28 August, the Johannes Kepler University Linz opened its doors for the twentieth time to host researchers convening to discuss the latest developments in alternatives to animal testing. This year’s focus included lab-on-a-chip systems, test strategies, stem cells and replacement methods for vaccines and biologicals, but also methods for refining animal tests. 

CAAT Academy Hands-on-Training in Vienna

Monday, 05 September 2016 07:18

In September, the CAAT Academy is organising a two-days hands-on-training on replacement methods to animal use. This course is about kidney toxicity.

The Extended One-Generation Reproductive Toxicity Study (EOGRTS) is a modular test method for reproductive toxicity. The document explains how ECHA identifies and concludes on the design of EOGRT under dossier evaluation.

EPAA 3Rs Science Prize: Call for submissions

Friday, 02 September 2016 07:36

In 2016, the EPAA partners will grant a prize of €10,000 for already achieved research, or a project at the completion stage with outstanding results in promoting Replacement, Reduction and Refinement (the 3Rs) of animal testing.

The webinar focuses on the standard information requirements for REACH registration, including the following endpoints:


Monday, 27 June 2016 11:19

The European Partnership for Alternative Approaches to Animal Testing (EPAA) launches its call to apply for the 2016 3Rs Science Prize. This year, the EPAA will grant a Prize for already achieved research, or a project already at the completion stage with outstanding results. The price money is € 10,000.