ECHA has published advice on how to use the OECD test guideline on fish embryo acute toxicity (FET) test under REACH. The document describes the scope and the limitations when using the FET test.

As the only state Baden-Württemberg annually supports the development of alternatives to animal experiments with 400,000 euros. In this round, three scientists are promoted for their development of in vitro methods and another project will be financed to improve welfare conditions of mice.

The virologists Prof. Ralf Bartenschlager from the Heidelberg University and two American colleagues will be awarded the highest medical and scientific award of the USA, the Lasker-DeBakey Clinical Medical Research Award. The award is regarded as the unofficial "American Nobel Prize in Medicine". The scientists will be honored for their long-lasting research on breeding of hepatitis C virus in cell culture systems.

Professor Anthony Atala from Institute of Regenerative Medicine at Wake Forest School of Medicine in North Carolina is a specialist in the field of regenerative medicine. But his subject is also miniorgans-on-a-chip: Together with his team he is already able to cultivate 12 different tissue types on the chip.

The Hebrew University in Jerusalem, headed by Prof. Michal Goldberg and Prof. Nissim Benvenisty together with researchers from Heinrich Heine University in Dusseldorf, headed by Prof. James Adjaye, have uncovered a signalling pathway mechanism which is responsible for the formation of microcephaly. This disease picture is one of several that may occur in the genetic Nijmegen breakage syndrome (NBS).

Basic researchers from Excellenzcluster CNMPB in Göttingen led by Prof. Gerhard Braus use yeast cells to study cellular mechanisms of Morbus Parkinson. They got new insights about pathogenic processes.

To investigate heart rhythm disturbances in vitro, researchers led by Dr. Daniel Sinnecker from the Technical University of Munich have integrated an optical sensor in heart cells in order to distinguish heart cell types by their electric potential from each other. The heart cells are produced from patients´ induced pluripotent stem cells.

The updated guide on How to use and report (Q)SARs, published in July in English, has been translated to 22 EU languages. It provides an overview of the important aspects to consider when predicting properties of substances using (Q)SAR models and gives useful examples of good prediction practices.

From 24 to 28 August, the Johannes Kepler University Linz opened its doors for the twentieth time to host researchers convening to discuss the latest developments in alternatives to animal testing. This year’s focus included lab-on-a-chip systems, test strategies, stem cells and replacement methods for vaccines and biologicals, but also methods for refining animal tests. 

CAAT Academy Hands-on-Training in Vienna

Monday, 05 September 2016 07:18

In September, the CAAT Academy is organising a two-days hands-on-training on replacement methods to animal use. This course is about kidney toxicity.