Using cell cultures, a German-Lebanese research team has done research into biochemical fundamental of the hereditary Niemann-Pick type C disease. They were able to clarify the relationship between different gene mutations and the function of a cholesterol transporter.

As part of their basic research into antibiotic resistance, scientists from the University of Greifswald studied the mechanism of a dangerous protein produced by the bacterium Staphylococcus aureus in more detail. For their research, they used human respiratory cells.

Using organoids, scientists from the Max Planck Institute for Infection Biology in Berlin have investigated the mechanism of chronic infection with chlamydia in fallopian tube cells and gained important insights.

Scientist at the National Center for Translational Science (NCATS) at the NIH in Washington, D. C., want to use organ-on-a-chip systems of the start-up company Hesperos to identify the causes of the national opioid crisis.

Heterotopia model in the Petri dish

Wednesday, 20 March 2019 14:49

Scientists at the Max Planck Institute for Psychiatry have used brain organoids to simulate the hereditary disease heterotopia. During brain development, cell migration disorders lead to node-like accumulations of grey matter outside the cerebral cortex.

Organ-on-Chip applications in Basic Research, Pharmaceutical Drug Development, Safety assessment of Drugs, Cosmetics and Chemicals among others are facing an exponential arise in interest. Therefore, specific training is required on the production of such cell culture systems using advanced microfabrication techniques and adequate on-chip characterization of relevant cell functions.

A team of Swiss scientists from EAWAG in Dübendorf has developed a device that can be used to test the harmfulness of fragrances to the environment using intestinal cells. Thus, animal experiments in ecotoxicological experiments can be reduced. The device has also potential for drug development.

On Thursday, March 14th, there will be given a very interesting lecture on 3D printing of spherical organ-like systems at Institute of Biotechnology of the Technical University Berlin. The physician Dr. Vladimir Mironov from the Medical Sechenov University in Moscow will inform the audience about tissue spheroids as building blocks for robot-assisted biofabrication of three-dimensionally printed tissues.

Bf3R awards funding for feasibility studies

Wednesday, 06 March 2019 08:54

The German Centre for the Protection of Experimental Animals (Bf3R) awards funding for young scientists. The total budget is 350,000 euros with which up to 10 projects can be funded each year.

EPAA: 3Rs student's grants 2019

Tuesday, 26 February 2019 15:39

The European Partnership for Alternative Approaches to Animal Testing (EPAA) supports students doing outstanding work in alternative approaches to attend a high-profile scientific event.