In future it will be possible to produce economically antibodies, holding a key role in the investigation of biological and medical questions, without the use of animals in large numbers.

For the first time ever in the world, researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden, have produced a blood vessel from stem cells and then used it in an operation on a 10-year-old girl at the Sahlgrenska University Hospital.

Researchers in Bochum have produced an antibody that allows them to distinguish the numerous types of stem cells in the nervous system better than before.

Columbia Engineers Patch A Heart

Monday, 09 May 2011 17:01

Researchers at Columbia Engineering have established a new method to patch a damaged heart using a tissue-engineering platform that enables heart tissue to repair itself.

Cultex Laboratories GmbH, located in the Medical Park Hannover, has developed the CULTEX® RFS module, a precision instrument for direct exposure of cells from the respiratory tract. Mimicking the in vivo situation, bronchial epithelial cells for example can be treated with a wide range of test substances (individual gases, gas mixtures, particulate aerosols etc.).

Starting with this article, InvitroJobs will present scientists and their innovative research in a regular feature called “Working Group – a Portrait”.
We will focus on newly developed methods, their evaluation and their potential for reducing and where possible replacing animal experimentation according to the 3R principle of Russel & Burch (reduce, refine, replace). We start with two research groups from the Clinical Research Laboratory of the Paediatric Cardiac Surgery Department of Tübingen University Hospital, “Haemocompatibility” and “Pyrogen assay”. The introduction is followed by an interview with Dr. med. Stefan Fennrich.

The Bavarian Research Foundation is supporting a research project under the name of COSIR (Combination of Chemical-Optical Sensors with Image Recognition) with the goal of developing a system for continuous imaging of cell cultures with simultaneous oxygen and pH value measurements of the sample without any human intervention.

Scientists from the Institute for Chemical and Bioengineering of the ETH Zurich have developed an electrolysis procedure, adapted from a technique normally used for water purification, for the treatment of peri-implantitis.

Tissue-engineered urethras

Wednesday, 09 March 2011 16:25

A team of doctors from Mexico and the United States has been successful in engineering artificial urethras using the body´s own cells. The urethras are fully functional six years after transplant. The structure and function  are nearly the same as naturally grown tissue.

Scientists from the RWTH Aachen in cooperation with the Christian Albrecht University of Kiel (CAU) and the Scripps Research Institute (San Diego, USA) published a new stem cell research method without animal use in the magazine Nature Methods (6.3.11).