In an international project, scientists from the Joint Research Centre of the European Commission have collaborated on a high-quality ecotoxicological database called EnviroTox, which aims to improve the environmental risk assessment of chemicals.

The Environmental Protection Agency (EPA) has released an updated version of its List of Alternative Test Methods and Strategies (or New Approach Methodologies [NAMs]).

The University Hospital Hamburg-Eppendorf (UKE) establishes a professorship for 3R methods. For this purpose, there will be a start-up financing of 200,000 euros, half each from the UKE and the city.

Baden-Württemberg: 3R Center for Tübingen

Wednesday, 18 December 2019 12:31

In order to investigate alternative methods to animal experiments in medical research, the state Baden-Württenberg supports the establishment of a scientific 3R center. From 2020, The Ministry of Science, Research and Art supports the University of Tübingen with a W3 professorship and finances the establishment of a center for alternatives to animal experiments with 130,000 euros per year for an initial period of five years.

Two teams of prize winners were awarded this year's prize for research into substitute and supplementary methods for animal experiments in research and teaching in Berlin.

Using a liver-on-a-chip model, a team led by Dr. Geraldine Hamilton, scientific director of the start-up company Emulate from Boston, has investigated whether they are able to detect the toxicity of drugs at an early stage.

Prof. Thierry Soldati and his team from the Department of Biochemistry at the University of Geneva infected amoebae and amoeboid-mobile slime fungus cells to test new antibiotics and to reduce animal testing with mice.

According to Dr. Peter Theunissen from the Dutch Medicines Evaluation Board (CBG), in the foreseeable future, much fewer animals are used for the evaluation of the developmental toxicology effects of drugs. On behalf of the government, the CBG monitors the quality of pharmaceuticals and is involved in the preparation of guidelines for the pharmaceutical industry.

Scientists from the Institute of Anatomy and Cell Biology at the Julius Maximilian University Würzburg (JMU) succeeded a step further to complex organoids with blood vessels, immune cells, and connective tissue.

Amyloid fibrils: Different than thought

Thursday, 14 November 2019 12:20

For the first time, a German-American team of scientists has succeeded in isolating and investigating beta-amyloid fibrils from the human brain. These protein fibers are suspected of causing Alzheimer's disease and cerebral amyloid angiopathy.