Prof. James Adjaye, head of the Institute for Stem Cell Research and Regenerative Medicine in Düsseldorf, and the bioinformatician Wasco Wruck have carried out a meta-analysis of RNA sequence data from three Sars-Cov2 studies, in which human lung epithelial cells had been used.

InVitro+Jobs presents scientists and their innovative research in a regular feature called “Working Group – a Portrait”. We focus on newly developed methods, their evaluation, and their potential for reducing and where possible replacing animal experimentation according to the 3R principles of Russel & Burch (reduce, refine, replace). In this issue, we present a young spin-off from Jena, Dynamic42 GmbH.

MIT: Physiom-on-a-Chip model developed

Wednesday, 13 May 2020 21:49

Bioengineers from the laboratory of the Massachusetts Institute of Technology in Cambridge,  have developed a multi-tissue model to study the relationships between organs and the immune system.

Australian breast cancer researchers have discovered a new type of immune cells in the human breast gland, called ductus macrophages. These cells could play an important role in the fight against breast cancer.

3Rs Science Prize 2020: Call for submissions

Wednesday, 29 April 2020 09:07

The European Partnership for Alternatives Approaches to Animal Testing (EPAA) aims to promote the development, validation and acceptance of 3Rs alternative approaches (replacement, reduction and refinement of testing on animals). The 3Rs science prize is granted every two years to a scientist with an outstanding contribution to the 3Rs.

Infection Research with Alveolar Organoids

Wednesday, 22 April 2020 14:52

Scientists at the Max Planck Institute for Infection Biology in Berlin led by Prof. Thomas F. Meyer, in cooperation with Prof. Andreas Hocke from the Charité University Hospital in Berlin, have developed an in vitro model of the human lung epithelium in 2018, that can currently be used for drug research against the coronavirus Sars-CoV-2.

Researchers at the Eberhard Karls University of Tübingen and at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have developed a new organ on a chip: the white fatty tissue on the chip (WAT-on-a-Chip).

Is Covid-19 starting in precursor cells?

Wednesday, 15 April 2020 21:28

Scientists from the Berlin Institute of Health (BIH), Charité University Medicine Berlin and the Thorax Clinic of the University Hospital Heidelberg have used non-infected lung cells from a lung biobank to find out which cell types of the lung and bronchia are preferentially affected by the coronavirus.

In Silico researcher wanted

Wednesday, 15 April 2020 19:06

The Virtual Physiological Human Institute (VPHi) is looking for individuals that have expertise useful in combatting the COVID-19 challenge.

Together in silico against coronavirus

Wednesday, 15 April 2020 18:55

The page "in silico world" collects all initiatives of the In Silico community toward the fight against coronavirus.