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A team from the Max Delbrück Center in Berlin has used human muscle cells to find out how statins affect the development, growth and division of skeletal muscle cells. The results provide an indication for a preventive treatment to avoid side effects.

Berlin: 6th SummerSchool of the BB3R

Friday, 14 February 2020 15:08

For the 6th time, the Berlin-Brandenburg 3R Platform (BB3R) is organizing a graduate college (summer school). Under the heading "Ethical and legal aspects and 3R approaches", doctoral students, postdocs and interested scientists are invited to participate.

Researchers from the Berlin Institute of Health (BIH), from the Charité - Universitätsmedizin Berlin as well as from the University Hospital in Heidelberg have developed a model that enables them to improve the accuracy of the CRISPR/Cas9 gen-scissors.

Engineers headed by Ellen Roche, assistant professor of mechanical engineering at MIT, have developed a bionic "heart". It is a more realistic model for testing of artificial heart valves and other heart devices than experiments on animals.

The European Commission has published reports on the numbers of animal experiments carried out in the member states for the years 2015-2017.

The Alternatives Research and Development Foundation (ARDF) awards grants to support research projects that develop alternative methods to advance science and replace or reduce animal use. ARDF is currently accepting applications for this year’s grants, with proposals due May 1.

A team led by Prof. Donald Ingber from the Wyss Institute for Biologically Inspired Engineering at Harvard University, Boston, has worked with the group of Dr. Kevin Kit Parker from the Harvard Stem Cell Institute. Together they have published two articles in which they present a human-on-a-chip consisting of 10 organs. The model is suitable for better and faster drug testing.

The European Commission supports the introduction of individualized computer models and simulations for the development and evaluation of drugs and medical devices.

Forbes recently published an article "The future of Clinical Trials? Here is a simulation model of the heart" that presents the great results achieved by the Living Heart Project towards the development of an extensive computer simulation model of the human heart that can then be used to test different types of devices and medications and train people how to do different procedures.

In a project funded by the PETA International Science Consortium Ltd., scientists from the Institute of Biochemistry, Biotechnology and Bioinformatics at the Technical University of Braunschweig, Germany, as well as from the British National Institute for Biological Standards and Control (NIBSC), have developed human antibodies that neutralize the diphtheria toxin.