The researchers suppose that therefore the mitochondria will stop he energy supply step by step causing the dead of the nerve cells.
To study the scientists cultivated isolated mitochondria together with beta amyloids in order to investigate the disturbance of protein transport into the mitochondria. As next step they want study whether this kind of mitochondria protein blockade also occurs in neurons of patients suffering from Alzheimer´s.
Original publication:
Giovanna Cenini, Cornelia Rüb, Michael Bruderek und Wolfgang Voos; "Amyloid ß-peptides interfere with mitochondrial preprotein import competence by a coaggregation process"; Molecular Biology of the Cell; 2016
Source:
http://www.bionity.com/de/news/160052/alzheimer-toxine-legen-kraftwerke-der-zelle-lahm.html?WT.mc_id=ca0264