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Wednesday, 18 May 2016 12:15

Human gut model HuMiX represents actual conditions Featured

Scientists from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg led by Prof. Paul Wilmes, in collaboration with colleagues at the Luxembourg Institute of Health and the University of Arizona in the United States have developed a model of the human gut which is representative of the actual conditions and processes that occur within humans´ intestines.

The apparatus, no bigger than a beer mat, consists of three chambers. The top chamber is the supply level, from which nutrients continuously flow down to the cell cultures below. Human cells grow on a very thin membrane in the middle chamber, while bacteria grow in the lowest chamber. With HuMiX, the researchers can analyse the complex interactions between human cells and bacteria, predict their effects on health or disease onset, and study the action of probiotics and drugs.

The researchers have published their findings in the journal Nature Communications (DOI: 10.1038/NCOMMS11535).

More information:
http://wwwen.uni.lu/forschung/highlights/darmmodell_humix_funktioniert_wie_das_natuerliche_vorbild
http://www.news-medical.net/news/20160511/Human-gut-model-HuMiX-represents-actual-conditions-processes-that-occr-within-intestines.aspx

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